The intensity of IUGR-induced transcriptome deregulations is inversely correlated with the onset of organ function in a rat model.

The intensity of IUGR-induced transcriptome deregulations is inversely correlated with the onset of organ function in a rat model.

A low-protein diet applied during pregnancy in the rat results in intrauterine growth restricted (IUGR) fetuses. In humans, IUGR is associated with increased perinatal morbidity, higher incidence of neuro-developmental defects and increased risk of adult metabolic anomalies, such as diabetes and car...

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Main Authors: Daniel Vaiman, Géraldine Gascoin-Lachambre, Farid Boubred, Françoise Mondon, Jean-Marc Feuerstein, Isabelle Ligi, Isabelle Grandvuillemin, Sandrine Barbaux, Eric Ghigo, Vincent Achard, Umberto Simeoni, Christophe Buffat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3120850?pdf=render

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http://europepmc.org/articles/PMC3120850?pdf=render

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