Subtyping of circulating exosome-bound amyloid β reflects brain plaque deposition

Subtyping of circulating exosome-bound amyloid β reflects brain plaque deposition

Detecting Alzheimer’s disease from blood samples is challenging because amyloid β blood levels are lower than the ELISA detection limit. Here the authors capture amyloid β bound to circulating exosomes on a plasmonic nanosensor, followed by enzymatic amplification to improve detection sensitivity....

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Bibliographic Details
Main Authors: Carine Z. J. Lim, Yan Zhang, Yu Chen, Haitao Zhao, Mary C. Stephenson, Nicholas R. Y. Ho, Yuan Chen, Jaehoon Chung, Anthonin Reilhac, Tze Ping Loh, Christopher L. H. Chen, Huilin Shao
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09030-2

Internet

https://doi.org/10.1038/s41467-019-09030-2

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