Timing of fluoride toothpaste use and enamel-dentin demineralization

It is well established that fluoride (F) prevents caries development by inhibiting demineralization and enhancing remineralization processes. However, it is not known which of these protective mechanisms is more important. In this double-blind, crossover in situ study conducted in three phases of 14...

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Main Authors: Sandro Carvalho Kusano, Livia Maria Andaló Tenuta, Altair Antoninha Del Bel Cury, Jaime Aparecido Cury
Format: Article
Language:English
Published: Sociedade Brasileira de Pesquisa Odontológica 2011-10-01
Series:Brazilian Oral Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242011000500002
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spelling doaj-def2a577b52a4520a25afe791713f4962020-11-24T23:53:10ZengSociedade Brasileira de Pesquisa Odontológica Brazilian Oral Research1806-83242011-10-0125538338710.1590/S1806-83242011000500002Timing of fluoride toothpaste use and enamel-dentin demineralizationSandro Carvalho KusanoLivia Maria Andaló TenutaAltair Antoninha Del Bel CuryJaime Aparecido CuryIt is well established that fluoride (F) prevents caries development by inhibiting demineralization and enhancing remineralization processes. However, it is not known which of these protective mechanisms is more important. In this double-blind, crossover in situ study conducted in three phases of 14 days each, 12 volunteers wore palatal appliances containing enamel and root dentin slabs, on which biofilm was allowed to accumulate under exposure to 20% sucrose solution 8×/day. F toothpaste was used once a day, either before the daily demineralizing episodes (in the morning) or after them (at night). Non-F placebo toothpaste was used in the control group. F toothpaste significantly reduced enamel and dentin demineralization compared with the control (p < 0.05). F toothpaste was more effective when used after the demineralization episodes than before, and this difference was statistically significant for dentin (p < 0.05). The results suggest that brushing with F dentifrice at night to remineralize daily mineral losses may be preferable to brushing in the morning to inhibit the demineralizing episodes of the day.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242011000500002DemineralizationDentifriceFluoridesDental EnamelDentin
collection DOAJ
language English
format Article
sources DOAJ
author Sandro Carvalho Kusano
Livia Maria Andaló Tenuta
Altair Antoninha Del Bel Cury
Jaime Aparecido Cury
spellingShingle Sandro Carvalho Kusano
Livia Maria Andaló Tenuta
Altair Antoninha Del Bel Cury
Jaime Aparecido Cury
Timing of fluoride toothpaste use and enamel-dentin demineralization
Brazilian Oral Research
Demineralization
Dentifrice
Fluorides
Dental Enamel
Dentin
author_facet Sandro Carvalho Kusano
Livia Maria Andaló Tenuta
Altair Antoninha Del Bel Cury
Jaime Aparecido Cury
author_sort Sandro Carvalho Kusano
title Timing of fluoride toothpaste use and enamel-dentin demineralization
title_short Timing of fluoride toothpaste use and enamel-dentin demineralization
title_full Timing of fluoride toothpaste use and enamel-dentin demineralization
title_fullStr Timing of fluoride toothpaste use and enamel-dentin demineralization
title_full_unstemmed Timing of fluoride toothpaste use and enamel-dentin demineralization
title_sort timing of fluoride toothpaste use and enamel-dentin demineralization
publisher Sociedade Brasileira de Pesquisa Odontológica
series Brazilian Oral Research
issn 1806-8324
publishDate 2011-10-01
description It is well established that fluoride (F) prevents caries development by inhibiting demineralization and enhancing remineralization processes. However, it is not known which of these protective mechanisms is more important. In this double-blind, crossover in situ study conducted in three phases of 14 days each, 12 volunteers wore palatal appliances containing enamel and root dentin slabs, on which biofilm was allowed to accumulate under exposure to 20% sucrose solution 8×/day. F toothpaste was used once a day, either before the daily demineralizing episodes (in the morning) or after them (at night). Non-F placebo toothpaste was used in the control group. F toothpaste significantly reduced enamel and dentin demineralization compared with the control (p < 0.05). F toothpaste was more effective when used after the demineralization episodes than before, and this difference was statistically significant for dentin (p < 0.05). The results suggest that brushing with F dentifrice at night to remineralize daily mineral losses may be preferable to brushing in the morning to inhibit the demineralizing episodes of the day.
topic Demineralization
Dentifrice
Fluorides
Dental Enamel
Dentin
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242011000500002
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