Interleukin-7 influences FOXP3+CD4+ regulatory T cells peripheral homeostasis.

Interleukin-7 influences FOXP3+CD4+ regulatory T cells peripheral homeostasis.

Mechanisms governing peripheral CD4+ FOXP3+ regulatory T cells (Treg) survival and homeostasis are multiple suggesting tight and complex regulation of regulatory T cells homeostasis. Some specific factors, such as TGF-β, interleukin-2 (IL-2) and B7 costimulatory molecules have been identified as ess...

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Bibliographic Details
Main Authors: Federico Simonetta, Nicolas Gestermann, Kim Zita Martinet, Michele Boniotto, Pierre Tissières, Benedict Seddon, Christine Bourgeois
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3346843?pdf=render

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http://europepmc.org/articles/PMC3346843?pdf=render

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