No association of CDK5 genetic variants with Alzheimer's disease risk

<p>Abstract</p> <p>Background</p> <p>As cyclin-dependent kinase 5 (CDK5) has been implicated in the abnormal hyperphosphorylation of tau in Alzheimer's disease (AD) brain, and the development of neurofibrillary tangles, we examined the contribution of this gene to...

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Bibliographic Details
Main Authors: Combarros Onofre, Berciano José, Infante Jon, Rodríguez-Rodríguez Eloy, Sánchez-Juan Pascual, Mateo Ignacio, Vázquez-Higuera José
Format: Article
Language:English
Published: BMC 2009-07-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/10/68