Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1

Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1

Both pathogen- and tissue damage-associated molecular patterns induce inflammation through toll-like receptors (TLRs), while sialic acid-binding immunoglobulin superfamily lectin receptors (Siglecs) provide negative regulation. Here we report extensive and direct interactions between these pattern r...

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Bibliographic Details
Main Authors: Guo-Yun Chen, Nicholas K Brown, Wei Wu, Zahra Khedri, Hai Yu, Xi Chen, Diantha van de Vlekkert, Alessandra D'Azzo, Pan Zheng, Yang Liu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-09-01
Series:eLife
Subjects:
Siglec
toll-like receptor
sialidase
Online Access:https://elifesciences.org/articles/04066

Internet

https://elifesciences.org/articles/04066

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