Sleeve Gastrectomy and Roux-En-Y Gastric Bypass. Two Sculptors of the Pancreatic Islet

Several surgical procedures are performed for the treatment of obesity. A main outcome of these procedures is the improvement of type 2 diabetes mellitus. Trying to explain this, gastrointestinal hormone levels and their effect on organs involved in carbohydrate metabolism, such as liver, gut, muscl...

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Main Authors:	Gonzalo-Martín Pérez-Arana, José Fernández-Vivero, Alonso Camacho-Ramírez, Alfredo Díaz Gómez, José Bancalero de los Reyes, Antonio Ribelles-García, David Almorza-Gomar, Carmen Carrasco-Molinillo, José-Arturo Prada-Oliveira
Format:	Article
Language:	English
Published:	MDPI AG 2021-09-01
Series:	Journal of Clinical Medicine
Subjects:	sleeve gastrectomy roux-en-Y gastric bypass beta-cell alpha-cell epsilon-cell islet
Online Access:	https://www.mdpi.com/2077-0383/10/18/4217

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spelling	doaj-df6ef85baa9240458a2081265b938b502021-09-26T00:28:39ZengMDPI AGJournal of Clinical Medicine2077-03832021-09-01104217421710.3390/jcm10184217Sleeve Gastrectomy and Roux-En-Y Gastric Bypass. Two Sculptors of the Pancreatic IsletGonzalo-Martín Pérez-Arana0José Fernández-Vivero1Alonso Camacho-Ramírez2Alfredo Díaz Gómez3José Bancalero de los Reyes4Antonio Ribelles-García5David Almorza-Gomar6Carmen Carrasco-Molinillo7José-Arturo Prada-Oliveira8Department of Human Anatomy and Embryology, Faculty of Medicine, University of Cadiz, 11003 Cadiz, SpainDepartment of Human Anatomy and Embryology, Faculty of Medicine, University of Cadiz, 11003 Cadiz, SpainDepartment of Human Anatomy and Embryology, Faculty of Medicine, University of Cadiz, 11003 Cadiz, SpainSan Carlos Hospital, Andalusian Health System, 28040 Madrid, SpainBadajoz Hospital, Extremadura Health System, 06001 Badajoz, SpainDepartment of Human Anatomy and Embryology, Faculty of Medicine, University of Cadiz, 11003 Cadiz, SpainInstitute for Biomedical Science Research and Innovation (INIBICA), University of Cadiz, 11003 Cadiz, SpainDepartment of Human Anatomy and Embryology, Faculty of Medicine, University of Cadiz, 11003 Cadiz, SpainDepartment of Human Anatomy and Embryology, Faculty of Medicine, University of Cadiz, 11003 Cadiz, SpainSeveral surgical procedures are performed for the treatment of obesity. A main outcome of these procedures is the improvement of type 2 diabetes mellitus. Trying to explain this, gastrointestinal hormone levels and their effect on organs involved in carbohydrate metabolism, such as liver, gut, muscle or fat, have been studied intensively after bariatric surgery. These effects on endocrine-cell populations in the pancreas have been less well studied. We gathered the existing data on these pancreatic-cell populations after the two most common types of bariatric surgery, the sleeve gastrectomy (SG) and the roux-en-Y gastric bypass (RYGB), with the aim to explain the pathophysiological mechanisms underlying these surgeries and to improve their outcome.https://www.mdpi.com/2077-0383/10/18/4217sleeve gastrectomyroux-en-Y gastric bypassbeta-cellalpha-cellepsilon-cellislet
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Gonzalo-Martín Pérez-Arana José Fernández-Vivero Alonso Camacho-Ramírez Alfredo Díaz Gómez José Bancalero de los Reyes Antonio Ribelles-García David Almorza-Gomar Carmen Carrasco-Molinillo José-Arturo Prada-Oliveira
spellingShingle	Gonzalo-Martín Pérez-Arana José Fernández-Vivero Alonso Camacho-Ramírez Alfredo Díaz Gómez José Bancalero de los Reyes Antonio Ribelles-García David Almorza-Gomar Carmen Carrasco-Molinillo José-Arturo Prada-Oliveira Sleeve Gastrectomy and Roux-En-Y Gastric Bypass. Two Sculptors of the Pancreatic Islet Journal of Clinical Medicine sleeve gastrectomy roux-en-Y gastric bypass beta-cell alpha-cell epsilon-cell islet
author_facet	Gonzalo-Martín Pérez-Arana José Fernández-Vivero Alonso Camacho-Ramírez Alfredo Díaz Gómez José Bancalero de los Reyes Antonio Ribelles-García David Almorza-Gomar Carmen Carrasco-Molinillo José-Arturo Prada-Oliveira
author_sort	Gonzalo-Martín Pérez-Arana
title	Sleeve Gastrectomy and Roux-En-Y Gastric Bypass. Two Sculptors of the Pancreatic Islet
title_short	Sleeve Gastrectomy and Roux-En-Y Gastric Bypass. Two Sculptors of the Pancreatic Islet
title_full	Sleeve Gastrectomy and Roux-En-Y Gastric Bypass. Two Sculptors of the Pancreatic Islet
title_fullStr	Sleeve Gastrectomy and Roux-En-Y Gastric Bypass. Two Sculptors of the Pancreatic Islet
title_full_unstemmed	Sleeve Gastrectomy and Roux-En-Y Gastric Bypass. Two Sculptors of the Pancreatic Islet
title_sort	sleeve gastrectomy and roux-en-y gastric bypass. two sculptors of the pancreatic islet
publisher	MDPI AG
series	Journal of Clinical Medicine
issn	2077-0383
publishDate	2021-09-01
description	Several surgical procedures are performed for the treatment of obesity. A main outcome of these procedures is the improvement of type 2 diabetes mellitus. Trying to explain this, gastrointestinal hormone levels and their effect on organs involved in carbohydrate metabolism, such as liver, gut, muscle or fat, have been studied intensively after bariatric surgery. These effects on endocrine-cell populations in the pancreas have been less well studied. We gathered the existing data on these pancreatic-cell populations after the two most common types of bariatric surgery, the sleeve gastrectomy (SG) and the roux-en-Y gastric bypass (RYGB), with the aim to explain the pathophysiological mechanisms underlying these surgeries and to improve their outcome.
topic	sleeve gastrectomy roux-en-Y gastric bypass beta-cell alpha-cell epsilon-cell islet
url	https://www.mdpi.com/2077-0383/10/18/4217
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Sleeve Gastrectomy and Roux-En-Y Gastric Bypass. Two Sculptors of the Pancreatic Islet

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