Striatal iron content is linked to reduced fronto-striatal brain function under working memory load

Non-heme iron accumulation contributes to age-related decline in brain structure and cognition via a cascade of oxidative stress and inflammation, although its effect on brain function is largely unexplored. Thus, we examine the impact of striatal iron on dynamic range of BOLD modulation to working...

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Bibliographic Details
Main Authors: Karen M. Rodrigue, Ana M. Daugherty, Chris M. Foster, Kristen M. Kennedy
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:NeuroImage
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811920300318