G-protein coupled receptor 83 (GPR83) signaling determined by constitutive and zinc(II)-induced activity.

The G-protein coupled receptor 83 (GPR83) is an orphan G-protein coupled receptor for which the natural ligand(s) and signaling pathway(s) remain to be identified. Previous studies suggest a role of GPR83 in the regulation of thermogenesis and the control of circulating adiponectin. The aim of this...

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Bibliographic Details
Main Authors: Anne Müller, Gunnar Kleinau, Carolin L Piechowski, Timo D Müller, Brian Finan, Juliane Pratzka, Annette Grüters, Heiko Krude, Matthias Tschöp, Heike Biebermann
Format: Article
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3546042?pdf=render