Recombination machinery engineering for precise genome editing in methylotrophic yeast Ogataea polymorpha

Summary: Methanol biotransformation can expand biorefinery substrate spectrum other than biomass by using methylotrophic microbes. Ogataea (Hansenula) polymorpha, a representative methylotrophic yeast, attracts much attention due to its thermotolerance, but the low homologous recombination (HR) effi...

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Bibliographic Details
Main Authors: Jiaoqi Gao, Ning Gao, Xiaoxin Zhai, Yongjin J. Zhou
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422100136X