Type 2 Innate Lymphocytes Actuate Immunity Against Tumours and Limit Cancer Metastasis

Abstract Type 2 innate lymphoid cells (ILC2) potentiate immune responses, however, their role in mediating adaptive immunity in cancer has not been assessed. Here, we report that mice genetically lacking ILC2s have significantly increased tumour growth rates and conspicuously higher frequency of cir...

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Bibliographic Details
Main Authors: Iryna Saranchova, Jeffrey Han, Rysa Zaman, Hitesh Arora, Hui Huang, Franz Fenninger, Kyung Bok Choi, Lonna Munro, Cheryl G. Pfeifer, Ian Welch, Fumio Takei, Wilfred A. Jefferies
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-20608-6