Resistance to deltamethrin by domestic and wild Triatoma infestans populations in the municipality of Toro Toro, Potosi, Bolivia
Abstract Background Chemical control with pyrethroid insecticides has been effective in reducing endemic areas of distribution of Triatoma infestans in the Southern Cone, as well as Bolivia; this had considerably reduced the infestation of households in a large part of the territory. Nowadays, areas...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2018-02-01
|
Series: | Parasites & Vectors |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13071-018-2663-5 |
id |
doaj-e0b2425731a848ee9c1e764b1682415d |
---|---|
record_format |
Article |
spelling |
doaj-e0b2425731a848ee9c1e764b1682415d2020-11-24T23:07:02ZengBMCParasites & Vectors1756-33052018-02-011111710.1186/s13071-018-2663-5Resistance to deltamethrin by domestic and wild Triatoma infestans populations in the municipality of Toro Toro, Potosi, BoliviaJorge Espinoza Echeverria0Marinely B. Bustamante Gomez1Grasielle Caldas D Ávila Pessoa2Mirko Rojas Cortez3Antonio Nogales Rodriguez4Liléia Gonçalves Diotaiuti5Laboratório de Referência Triatomíneos e Epidemiologia da Doença de Chagas, Centro de Pesquisas René Rachou, FIOCRUZ-M GLaboratório de Referência Triatomíneos e Epidemiologia da Doença de Chagas, Centro de Pesquisas René Rachou, FIOCRUZ-M GLaboratório de Referência Triatomíneos e Epidemiologia da Doença de Chagas, Centro de Pesquisas René Rachou, FIOCRUZ-M GCEADES Salud y Medio Ambiente/Plataforma ChagasServicio Departamental de Salud - Potosi, Programa Nacional de ChagasLaboratório de Referência Triatomíneos e Epidemiologia da Doença de Chagas, Centro de Pesquisas René Rachou, FIOCRUZ-M GAbstract Background Chemical control with pyrethroid insecticides has been effective in reducing endemic areas of distribution of Triatoma infestans in the Southern Cone, as well as Bolivia; this had considerably reduced the infestation of households in a large part of the territory. Nowadays, areas such as the Chaco and the Inter-Andean Valleys are regions where the reach of vector control strategies is becoming limited, and infestations of insecticide-treated households are reported more often. The objective of this study was to determine if the persistence of T. infestans stems from changes in the susceptibility of its toxicological profile in four communities in the municipality of Toro Toro, Potosi, Bolivia. Methods Susceptibility to deltamethrin of wild and domestic populations of T. infestans was evaluated in two stages (16 populations before and 13 populations after spraying) among DUs (structures in the intra- and peridomicile) and wild ecotopes, in four communities. Serial dilutions of deltamethrin in acetone (0.2 μl) were applied topically on standardized first-stage nymphs. Dose-response results were analyzed with the software PoloPlus and the relationships between lethal doses (LD) and resistance ratios (RR50) were determined. Results Different degrees of RR50 were detected among the populations before and after spraying (25.66–54.70 and 21.91–40.67, respectively), as well as in different ecotopes within a DU (DU JC 3, 28.06–36.13, in mixed structures of corrals and chicken coops; and DU JG 3, 46.27–25.70, in kitchen roofs), or in the wild environment of the community JG Sil (29.21–40.67). The mortality of insects undergoing diagnostic dose (DD) was never higher than 34%. Conclusion The results obtained in this study showed resistance of T. infestans to deltamethrin in four communities, hence the complexity of this phenomenon is not only limited to the level of communities, but also applies to the microgeographical level, as in different ecotopes present within the DUs. This phenomenon should be considered while planning the activities of control programs.http://link.springer.com/article/10.1186/s13071-018-2663-5Triatoma infestansBoliviaChagas diseaseInsecticide resistanceDeltamethrinMacro- and microgeography |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jorge Espinoza Echeverria Marinely B. Bustamante Gomez Grasielle Caldas D Ávila Pessoa Mirko Rojas Cortez Antonio Nogales Rodriguez Liléia Gonçalves Diotaiuti |
spellingShingle |
Jorge Espinoza Echeverria Marinely B. Bustamante Gomez Grasielle Caldas D Ávila Pessoa Mirko Rojas Cortez Antonio Nogales Rodriguez Liléia Gonçalves Diotaiuti Resistance to deltamethrin by domestic and wild Triatoma infestans populations in the municipality of Toro Toro, Potosi, Bolivia Parasites & Vectors Triatoma infestans Bolivia Chagas disease Insecticide resistance Deltamethrin Macro- and microgeography |
author_facet |
Jorge Espinoza Echeverria Marinely B. Bustamante Gomez Grasielle Caldas D Ávila Pessoa Mirko Rojas Cortez Antonio Nogales Rodriguez Liléia Gonçalves Diotaiuti |
author_sort |
Jorge Espinoza Echeverria |
title |
Resistance to deltamethrin by domestic and wild Triatoma infestans populations in the municipality of Toro Toro, Potosi, Bolivia |
title_short |
Resistance to deltamethrin by domestic and wild Triatoma infestans populations in the municipality of Toro Toro, Potosi, Bolivia |
title_full |
Resistance to deltamethrin by domestic and wild Triatoma infestans populations in the municipality of Toro Toro, Potosi, Bolivia |
title_fullStr |
Resistance to deltamethrin by domestic and wild Triatoma infestans populations in the municipality of Toro Toro, Potosi, Bolivia |
title_full_unstemmed |
Resistance to deltamethrin by domestic and wild Triatoma infestans populations in the municipality of Toro Toro, Potosi, Bolivia |
title_sort |
resistance to deltamethrin by domestic and wild triatoma infestans populations in the municipality of toro toro, potosi, bolivia |
publisher |
BMC |
series |
Parasites & Vectors |
issn |
1756-3305 |
publishDate |
2018-02-01 |
description |
Abstract Background Chemical control with pyrethroid insecticides has been effective in reducing endemic areas of distribution of Triatoma infestans in the Southern Cone, as well as Bolivia; this had considerably reduced the infestation of households in a large part of the territory. Nowadays, areas such as the Chaco and the Inter-Andean Valleys are regions where the reach of vector control strategies is becoming limited, and infestations of insecticide-treated households are reported more often. The objective of this study was to determine if the persistence of T. infestans stems from changes in the susceptibility of its toxicological profile in four communities in the municipality of Toro Toro, Potosi, Bolivia. Methods Susceptibility to deltamethrin of wild and domestic populations of T. infestans was evaluated in two stages (16 populations before and 13 populations after spraying) among DUs (structures in the intra- and peridomicile) and wild ecotopes, in four communities. Serial dilutions of deltamethrin in acetone (0.2 μl) were applied topically on standardized first-stage nymphs. Dose-response results were analyzed with the software PoloPlus and the relationships between lethal doses (LD) and resistance ratios (RR50) were determined. Results Different degrees of RR50 were detected among the populations before and after spraying (25.66–54.70 and 21.91–40.67, respectively), as well as in different ecotopes within a DU (DU JC 3, 28.06–36.13, in mixed structures of corrals and chicken coops; and DU JG 3, 46.27–25.70, in kitchen roofs), or in the wild environment of the community JG Sil (29.21–40.67). The mortality of insects undergoing diagnostic dose (DD) was never higher than 34%. Conclusion The results obtained in this study showed resistance of T. infestans to deltamethrin in four communities, hence the complexity of this phenomenon is not only limited to the level of communities, but also applies to the microgeographical level, as in different ecotopes present within the DUs. This phenomenon should be considered while planning the activities of control programs. |
topic |
Triatoma infestans Bolivia Chagas disease Insecticide resistance Deltamethrin Macro- and microgeography |
url |
http://link.springer.com/article/10.1186/s13071-018-2663-5 |
work_keys_str_mv |
AT jorgeespinozaecheverria resistancetodeltamethrinbydomesticandwildtriatomainfestanspopulationsinthemunicipalityoftorotoropotosibolivia AT marinelybbustamantegomez resistancetodeltamethrinbydomesticandwildtriatomainfestanspopulationsinthemunicipalityoftorotoropotosibolivia AT grasiellecaldasdavilapessoa resistancetodeltamethrinbydomesticandwildtriatomainfestanspopulationsinthemunicipalityoftorotoropotosibolivia AT mirkorojascortez resistancetodeltamethrinbydomesticandwildtriatomainfestanspopulationsinthemunicipalityoftorotoropotosibolivia AT antonionogalesrodriguez resistancetodeltamethrinbydomesticandwildtriatomainfestanspopulationsinthemunicipalityoftorotoropotosibolivia AT lileiagoncalvesdiotaiuti resistancetodeltamethrinbydomesticandwildtriatomainfestanspopulationsinthemunicipalityoftorotoropotosibolivia |
_version_ |
1725620433579933696 |