What is the best approach to reducing birth defects associated with isotretinoin?
BACKGROUND TO THE DEBATE: Isotretinoin is an effective treatment for severe acne, a condition which can be physically, emotionally, and socially disabling. Because the drug is teratogenic, causing severe birth defects, women taking the drug are directed to avoid pregnancy. In the United States, a se...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2006-11-01
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| Series: | PLoS Medicine |
| Online Access: | http://europepmc.org/articles/PMC1637125?pdf=render |