Cytotoxic Activity of the Mesoionic Compound MIH 2.4Bl in Breast Cancer Cell Lines

In this work, we report the synthesis of a new 1,3-thiazolium-5-thiolate derivative of a mesoionic compound (MIH 2.4Bl) and the characterization of its selective cytotoxicity on a panel of breast cancer cells lines. The cytotoxic effect of MIH 2.4Bl on breast cancer cell lines was determined by XTT...

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Main Authors: Luciana Amaral de Mascena Costa, Ashlyn C Harmon, Alvaro Aguiar Coelho Teixeira, Filipe Cássio Silva de Lima, Silvany de Sousa Araújo, Fabio Del Piero, Helivaldo Diógenes da Silva Souza, Petrônio Filgueiras de Athayde Filho, Severino Alves Junior, Maria de Mascena Diniz Maia, Aurea Wischral, Manoel Adrião Gomes Filho, J Michael Mathis
Format: Article
Language:English
Published: SAGE Publishing 2020-06-01
Series:Breast Cancer: Basic and Clinical Research
Online Access:https://doi.org/10.1177/1178223420913330