Natural Course of Clinically Isolated Syndrome: A Longitudinal Analysis Using a Markov Model
Abstract Clinically isolated syndrome (CIS) refers to the initial clinical episode with symptoms suggestive of multiple sclerosis (MS). Due to limited number of long-term follow-up studies, progression pattern from CIS to more advanced stages remains unclear. In the current study, we constructed a M...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-07-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-018-29206-y |