Halofuginone regulates keloid fibroblast fibrotic response to TGF-β induction

Keloids are characterized by increased deposition of fibrous tissue in the skin and subcutaneous tissue following an abnormal wound healing process. Although keloid etiology is yet to be fully understood, fibroblasts are known to be key players in its development. Here we analyze the antifibrotic me...

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Bibliographic Details
Main Authors: Pierre Marty, Brice Chatelain, Thomas Lihoreau, Marion Tissot, Zélie Dirand, Philippe Humbert, Clémence Senez, Eleonora Secomandi, Ciro Isidoro, Gwenaël Rolin
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220313755