Co-production of GroELS discriminates between intrinsic and thermally-induced recombinant protein aggregation during substrate quality control

<p>Abstract</p> <p>Background</p> <p>The effects and effectiveness of the chaperone pair GroELS on the yield and quality of recombinant polypeptides produced in <it>Escherichia coli </it>are matter of controversy, as the reported activities of this complex a...

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Bibliographic Details
Main Authors: Rodríguez-Carmona Escarlata, Platas Gemma, García-Fruitós Elena, Cano-Garrido Olivia, Villaverde Antonio
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Microbial Cell Factories
Online Access:http://www.microbialcellfactories.com/content/10/1/79