miR-29a sensitizes the response of glioma cells to temozolomide by modulating the P53/MDM2 feedback loop
Abstract Recently, pivotal functions of miRNAs in regulating common tumorigenic processes and manipulating signaling pathways in brain tumors have been recognized; notably, miR‐29a is closely associated with p53 signaling, contributing to the development of glioma. However, the molecular mechanism o...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-05-01
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Series: | Cellular & Molecular Biology Letters |
Subjects: | |
Online Access: | https://doi.org/10.1186/s11658-021-00266-9 |