miR-29a sensitizes the response of glioma cells to temozolomide by modulating the P53/MDM2 feedback loop

Abstract Recently, pivotal functions of miRNAs in regulating common tumorigenic processes and manipulating signaling pathways in brain tumors have been recognized; notably, miR‐29a is closely associated with p53 signaling, contributing to the development of glioma. However, the molecular mechanism o...

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Bibliographic Details
Main Authors: Qiudan Chen, Weifeng Wang, Shuying Chen, Xiaotong Chen, Yong Lin
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Cellular & Molecular Biology Letters
Subjects:
p53
Online Access:https://doi.org/10.1186/s11658-021-00266-9