Impact of Leptin on Periodontal Ligament Fibroblasts during Mechanical Strain

Orthodontic treatment to correct dental malocclusions leads to the formation of pressure zones in the periodontal ligament resulting in a sterile inflammatory reaction, which is mediated by periodontal ligament fibroblasts (PDLF). Leptin levels are elevated in obesity and chronic inflammatory respon...

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Bibliographic Details
Main Authors: Agnes Schröder, Andrea Meyer, Gerrit Spanier, Anna Damanaki, Eva Paddenberg, Peter Proff, Christian Kirschneck
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/13/6847