PGE2 displays immunosuppressive effects during human active tuberculosis

Abstract Prostaglandin E2 (PGE2), an active lipid compound derived from arachidonic acid, regulates different stages of the immune response of the host during several pathologies such as chronic infections or cancer. In fact, manipulation of PGE2 levels was proposed as an approach for countering the...

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Bibliographic Details
Main Authors: Joaquín Miguel Pellegrini, Candela Martin, María Paula Morelli, Julieta Aylen Schander, Nancy Liliana Tateosian, Nicolás Oscar Amiano, Agustín Rollandelli, Domingo Juan Palmero, Alberto Levi, Lorena Ciallella, María Isabel Colombo, Verónica Edith García
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92667-1