Differential Expression of Woodchuck Toll-Like Receptors 1–10 in Distinct Forms of Infection and Stages of Hepatitis in Experimental Hepatitis B Virus Infection

Differential Expression of Woodchuck Toll-Like Receptors 1–10 in Distinct Forms of Infection and Stages of Hepatitis in Experimental Hepatitis B Virus Infection

Woodchucks infected with woodchuck hepatitis virus (WHV) represent a highly valuable model of human hepatitis B virus (HBV) infection, chronic hepatitis (CH), and virus induced-primary liver cancer. Toll-like receptors (TLRs) are important mediators of immune responses playing pivotal roles in the p...

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Bibliographic Details
Main Authors: John Bradley Williams, Alena Hüppner, Patricia M. Mulrooney-Cousins, Tomasz I. Michalak
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Microbiology
Subjects:
woodchuck model of hepatitis B
hepadnaviral infection
toll-like receptors
liver
hepatocytes
PBMC
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.03007/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.03007/full

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