Linseed hydrogel based floating drug delivery system for fluoroquinolone antibiotics: Design, in vitro drug release and in vivo real-time floating detection

Herein, we designed a novel gastroretentive drug delivery system as floating matrix tablets based on a polysaccharide material from linseeds (Linum usitatissimum L.) for fluoroquinolone antibiotics. A number of formulations were designed with a combination of linseed hydrogel (LSH) and different exc...

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Bibliographic Details
Main Authors: Fatima Akbar Sheikh, Muhammad Ajaz Hussain, Muhammad Umer Ashraf, Muhammad Tahir Haseeb, Muhammad Farid-ul-Haq
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Saudi Pharmaceutical Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016420300608