Participation of TDP1 in the repair of formaldehyde-induced DNA-protein cross-links in chicken DT40 cells.
Proteins are covalently trapped on DNA to form DNA-protein cross-links (DPCs) when cells are exposed to DNA-damaging agents. Aldehyde compounds produce common types of DPCs that contain proteins in an undisrupted DNA strand. Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs topoisomerase 1 (TOPO1) that...
Main Authors: | Toshiaki Nakano, Mahmoud I Shoulkamy, Masataka Tsuda, Hiroyuki Sasanuma, Kouji Hirota, Minoru Takata, Shin-Ichiro Masunaga, Shunichi Takeda, Hiroshi Ide, Tadayoshi Bessho, Keizo Tano |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0234859 |
Similar Items
-
Selective cytotoxicity of the anti-diabetic drug, metformin, in glucose-deprived chicken DT40 cells.
by: Kei Kadoda, et al.
Published: (2017-01-01) -
PRDX1 is essential for the viability and maintenance of reactive oxygen species in chicken DT40
by: Takahito Moriwaki, et al.
Published: (2021-08-01) -
PRDX1 is essential for the viability and maintenance of reactive oxygen species in chicken DT40
by: Moriwaki, T., et al.
Published: (2021) -
Division of labor of Y-family polymerases in translesion-DNA synthesis for distinct types of DNA damage.
by: Yuriko Inomata, et al.
Published: (2021-01-01) -
Development of a targeted flip-in system in avian DT40 cells.
by: Kaori Kobayashi, et al.
Published: (2015-01-01)