Regulation of glioblastoma progression by cord blood stem cells is mediated by downregulation of cyclin D1.

The normal progression of the cell cycle requires sequential expression of cyclins. Rapid induction of cyclin D1 and its associated binding with cyclin-dependent kinases, in the presence or absence of mitogenic signals, often is considered a rate-limiting step during cell cycle progression through t...

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Bibliographic Details
Main Authors: Kiran Kumar Velpula, Venkata Ramesh Dasari, Andrew J Tsung, Christopher S Gondi, Jeffrey D Klopfenstein, Sanjeeva Mohanam, Jasti S Rao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3063796?pdf=render