Human Cytomegalovirus-Encoded G Protein-Coupled Receptor UL33 Facilitates Virus Dissemination via the Extracellular and Cell-to-Cell Route

Human Cytomegalovirus-Encoded G Protein-Coupled Receptor UL33 Facilitates Virus Dissemination via the Extracellular and Cell-to-Cell Route

Human cytomegalovirus (HCMV) encodes four G protein-coupled receptor (GPCR) homologs. Three of these receptors, UL78, US27 and US28, are known for their roles in HCMV dissemination and latency. Despite importance of its rodent orthologs for viral replication and pathogenesis, such a function is not...

Full description

Bibliographic Details
Main Authors: Jeffrey R. van Senten, Maarten P. Bebelman, Puck van Gasselt, Nick D. Bergkamp, Jelle van den Bor, Marco Siderius, Martine J. Smit
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Viruses
Subjects:
HCMV
cytomegalovirus
G protein-coupled receptor (GPCR)
chemokine receptor
7TM receptor
Online Access:https://www.mdpi.com/1999-4915/12/6/594

Internet

https://www.mdpi.com/1999-4915/12/6/594

Similar Items