Transcriptome Analysis of Monozygotic Twin Brothers with Childhood Primary Myelofibrosis

Transcriptome Analysis of Monozygotic Twin Brothers with Childhood Primary Myelofibrosis

Primary myelofibrosis (PMF) is a chronic myeloproliferative disorder in human bone marrow. Over 50% of patients with myelofibrosis have mutations in JAK2, MPL, or CALR. However, these mutations are rarely detected in children, suggesting a difference in the pathogenesis of childhood PMF. In this stu...

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Bibliographic Details
Main Authors: Nan Ding, Zhaojun Zhang, Wenyu Yang, Lan Ren, Yingchi Zhang, Jingliao Zhang, Zhanqi Li, Peihong Zhang, Xiaofan Zhu, Xiaojuan Chen, Xiangdong Fang
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Genomics, Proteomics & Bioinformatics
Subjects:
Primary myelofibrosis
RNA-seq
Apoptosis
Monozygotic twin
Childhood
Hematological disease
Online Access:http://www.sciencedirect.com/science/article/pii/S1672022917300049

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http://www.sciencedirect.com/science/article/pii/S1672022917300049

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