Spontaneous Cell Fusion of Acute Leukemia Cells and Macrophages Observed in Cells with Leukemic Potential

Spontaneous Cell Fusion of Acute Leukemia Cells and Macrophages Observed in Cells with Leukemic Potential

Cell fusion plays a well-recognized physiological role during development, while its function during progression is still unclear. Here, we show that acute myeloid leukemia (AML) cells spontaneously fused with murine host cells in vivo. AML cells fused in most cases with mouse macrophages. Other ta...

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Bibliographic Details
Main Authors: Ines Martin-Padura, Paola Marighetti, Giuliana Gregato, Alice Agliano, Omar Malazzi, Patrizia Mancuso, Giancarlo Pruneri, Andrea Viale, Francesco Bertolini
Format: Article
Language:English
Published: Elsevier 2012-11-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558612801175

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http://www.sciencedirect.com/science/article/pii/S1476558612801175

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