Reactive oxidants and myeloperoxidase and their involvement in neutrophil extracellular traps

Neutrophils release extracellular traps (NETs) in response to a variety of inflammatory stimuli. These structures are composed of a network of chromatin strands associated with a variety of neutrophil-derived proteins including the enzyme myeloperoxidase (MPO). Studies into the mechanisms leading...

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Bibliographic Details
Main Authors: Heather eParker, Christine eWinterbourn
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00424/full