Trapping a somatic endogenous retrovirus into a germline piRNA cluster immunizes the germline against further invasion

Trapping a somatic endogenous retrovirus into a germline piRNA cluster immunizes the germline against further invasion

Abstract Background For species survival, the germline must faithfully transmit genetic information to the progeny. Transposable elements (TEs) constitute a significant threat to genome stability due to their mobility. In the metazoan germline, their mobilization is limited by a class of small RNAs...

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Bibliographic Details
Main Authors: Céline Duc, Marianne Yoth, Silke Jensen, Nolwenn Mouniée, Casey M. Bergman, Chantal Vaury, Emilie Brasset
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Genome Biology
Subjects:
Transposable elements
piRNAs
piRNA cluster
Genome stability
Inheritance
Drosophila
Online Access:http://link.springer.com/article/10.1186/s13059-019-1736-x

Internet

http://link.springer.com/article/10.1186/s13059-019-1736-x

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