Evidence of microbial translocation associated with perturbations in T cell and antigen-presenting cell homeostasis in hookworm infections.

Microbial translocation (MT) is the process by which microbes or microbial products translocate from the intestine to the systemic circulation. MT is a common cause of systemic immune activation in HIV infection and is associated with reduced frequencies of CD4(+) T cells; no data exist, however, on...

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Bibliographic Details
Main Authors: Palakkal Jovvian George, Rajamanickam Anuradha, Nathella Pavan Kumar, Vasanthapuram Kumaraswami, Thomas B Nutman, Subash Babu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3464301?pdf=render