Association of PTPN22 1858C/T Polymorphism with Autoimmune Diseases: A Systematic Review and Bayesian Approach

Association of PTPN22 1858C/T Polymorphism with Autoimmune Diseases: A Systematic Review and Bayesian Approach

The 1858T allele in the protein tyrosine phosphatase non-receptor type 22 (PTPN22) locus shows one of the strongest and most consistent genetic associations with autoimmune diseases. We synthesized all meta-analyses reporting a genetic association of the PTPN22 1858T C/T polymorphism with autoimmune...

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Bibliographic Details
Main Authors: Kalthoum Tizaoui, Seon Hui Kim, Gwang Hun Jeong, Andreas Kronbichler, Kwang Seob Lee, Keum Hwa Lee, Jae Il Shin
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Journal of Clinical Medicine
Subjects:
autoimmune disease
single nucleotide polymorphism
PTPN22
false-positive report probability
Bayesian false discovery probability
genome wide association study
meta-analysis
Online Access:http://www.mdpi.com/2077-0383/8/3/347

Internet

http://www.mdpi.com/2077-0383/8/3/347

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