The two glycolytic markers GLUT1 and MCT1 correlate with tumor grade and survival in clear-cell renal cell carcinoma.

The two glycolytic markers GLUT1 and MCT1 correlate with tumor grade and survival in clear-cell renal cell carcinoma.

Clear-cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer. Although ccRCC is characterized by common recurrent genetic abnormalities, including inactivation of the von Hippel-Lindau (vhl) tumor suppressor gene resulting in stabilization of hypoxia-inducible factors (HIFs), the...

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Main Authors: Damien Ambrosetti, Maeva Dufies, Bérengère Dadone, Matthieu Durand, Delphine Borchiellini, Jean Amiel, Jacques Pouyssegur, Nathalie Rioux-Leclercq, Gilles Pages, Fanny Burel-Vandenbos, Nathalie M Mazure
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5826688?pdf=render

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http://europepmc.org/articles/PMC5826688?pdf=render

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