The kinematics of cytotoxic lymphocytes influence their ability to kill target cells.
Cytotoxic lymphocytes (CTL) have been reported to show a range of motility patterns from rapid long-range tracking to complete arrest, but how and whether these kinematics affect their ability to kill target cells is not known. Many in vitro killing assays utilize cell lines and tumour-derived cells...
Main Authors: | Purnima Bhat, Graham Leggatt, Klaus I Matthaei, Ian H Frazer |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4011687?pdf=render |
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