In silico approach to inhibition of signaling pathways of Toll-like receptors 2 and 4 by ST2L.

Toll-like receptors (TLRs) activate a potent immunostimulatory response. There is clear evidence that overactivation of TLRs leads to infectious and inflammatory diseases. Recent biochemical studies have shown that the membrane-bound form of ST2 (ST2L), a member of the Toll-like/IL-1 receptor superf...

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Bibliographic Details
Main Authors: Shaherin Basith, Balachandran Manavalan, Rajiv Gandhi Govindaraj, Sangdun Choi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3163686?pdf=render