Genetic evidence supporting the association of protease and protease inhibitor genes with inflammatory bowel disease: a systematic review.

As part of the European research consortium IBDase, we addressed the role of proteases and protease inhibitors (P/PIs) in inflammatory bowel disease (IBD), characterized by chronic mucosal inflammation of the gastrointestinal tract, which affects 2.2 million people in Europe and 1.4 million people i...

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Bibliographic Details
Main Authors: Isabelle Cleynen, Peter Jüni, Geertruida E Bekkering, Eveline Nüesch, Camila T Mendes, Stefanie Schmied, Stefan Wyder, Eliane Kellen, Peter M Villiger, Paul Rutgeerts, Séverine Vermeire, Daniel Lottaz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3169567?pdf=render