Variables associated with extra uterine growth restriction in very low birth weight infants

Objectives: To determine the rate of extrauterine growth restriction in very low birth weight infants and to evaluate the influence of perinatal variables, clinical practices, and neonatal morbidities on this outcome. Methods: A longitudinal study was performed in four neonatal units in the city of...

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Main Authors: Paola Azara Tabicas Lima, Manoel de Carvalho, Ana Carolina Carioca da Costa, Maria Elisabeth Lopes Moreira
Format: Article
Language:Portuguese
Published: Elsevier 2014-01-01
Series:Jornal de Pediatria (Versão em Português)
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2255553614000147
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spelling doaj-e7742aa2790f429fb7dcc35895e652ce2020-11-24T22:33:50ZporElsevierJornal de Pediatria (Versão em Português)2255-55362014-01-01901222710.1016/j.jpedp.2013.05.007Variables associated with extra uterine growth restriction in very low birth weight infantsPaola Azara Tabicas Lima0Manoel de Carvalho1Ana Carolina Carioca da Costa2Maria Elisabeth Lopes Moreira3Clínica Perinatal Laranjeiras, Rio de Janeiro, RJ, BrasilClínica Perinatal Laranjeiras, Rio de Janeiro, RJ, BrasilInstituto Fernandes Figueira/Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, RJ, BrazilClínica Perinatal Laranjeiras, Rio de Janeiro, RJ, BrasilObjectives: To determine the rate of extrauterine growth restriction in very low birth weight infants and to evaluate the influence of perinatal variables, clinical practices, and neonatal morbidities on this outcome. Methods: A longitudinal study was performed in four neonatal units in the city of Rio de Janeiro. 570 very low birth weight infants were analyzed. The study included perinatal variables, variables related to clinical practices, and incident morbidities in these preterm infants. Extrauterine growth restriction was defined using z-scores for weight or head circumference ≤ −2 for cor-rected age. Statistical analysis was performed using the Statistical Package for Social Sciences (SPSS) and R software. Results: This study comprised 570 infants, of which 49% were males, and 33% were small for gestational age (SGA). The mean weight and head circumference at birth were 1,113± 267 g and 27 ± 2 cm, respectively. The mean z-scores of birth weight and weight at discharge were −0.96± 0.78 and −1.54 ± 0.75, respectively; for head circumference, the mean z-scores at birth and at discharge were −0.63 ± 1.18 and −0.45 ± 0.94, respectively. The rate of extrauterine growth restriction considering the weight was 26% (149/570) and considering the head circumference, 5% (29/570). SGA was the variable with the greatest impact on both growth restriction for weight (PR = 4.33) and for head circumference (PR = 2.11) in adjusted analyses. Conclusion: Extrauterine growth restriction was high in the population, especially for SGA newborns and those with neonatal morbiditieshttp://www.sciencedirect.com/science/article/pii/S2255553614000147PrematureGrowthMalnutrition
collection DOAJ
language Portuguese
format Article
sources DOAJ
author Paola Azara Tabicas Lima
Manoel de Carvalho
Ana Carolina Carioca da Costa
Maria Elisabeth Lopes Moreira
spellingShingle Paola Azara Tabicas Lima
Manoel de Carvalho
Ana Carolina Carioca da Costa
Maria Elisabeth Lopes Moreira
Variables associated with extra uterine growth restriction in very low birth weight infants
Jornal de Pediatria (Versão em Português)
Premature
Growth
Malnutrition
author_facet Paola Azara Tabicas Lima
Manoel de Carvalho
Ana Carolina Carioca da Costa
Maria Elisabeth Lopes Moreira
author_sort Paola Azara Tabicas Lima
title Variables associated with extra uterine growth restriction in very low birth weight infants
title_short Variables associated with extra uterine growth restriction in very low birth weight infants
title_full Variables associated with extra uterine growth restriction in very low birth weight infants
title_fullStr Variables associated with extra uterine growth restriction in very low birth weight infants
title_full_unstemmed Variables associated with extra uterine growth restriction in very low birth weight infants
title_sort variables associated with extra uterine growth restriction in very low birth weight infants
publisher Elsevier
series Jornal de Pediatria (Versão em Português)
issn 2255-5536
publishDate 2014-01-01
description Objectives: To determine the rate of extrauterine growth restriction in very low birth weight infants and to evaluate the influence of perinatal variables, clinical practices, and neonatal morbidities on this outcome. Methods: A longitudinal study was performed in four neonatal units in the city of Rio de Janeiro. 570 very low birth weight infants were analyzed. The study included perinatal variables, variables related to clinical practices, and incident morbidities in these preterm infants. Extrauterine growth restriction was defined using z-scores for weight or head circumference ≤ −2 for cor-rected age. Statistical analysis was performed using the Statistical Package for Social Sciences (SPSS) and R software. Results: This study comprised 570 infants, of which 49% were males, and 33% were small for gestational age (SGA). The mean weight and head circumference at birth were 1,113± 267 g and 27 ± 2 cm, respectively. The mean z-scores of birth weight and weight at discharge were −0.96± 0.78 and −1.54 ± 0.75, respectively; for head circumference, the mean z-scores at birth and at discharge were −0.63 ± 1.18 and −0.45 ± 0.94, respectively. The rate of extrauterine growth restriction considering the weight was 26% (149/570) and considering the head circumference, 5% (29/570). SGA was the variable with the greatest impact on both growth restriction for weight (PR = 4.33) and for head circumference (PR = 2.11) in adjusted analyses. Conclusion: Extrauterine growth restriction was high in the population, especially for SGA newborns and those with neonatal morbidities
topic Premature
Growth
Malnutrition
url http://www.sciencedirect.com/science/article/pii/S2255553614000147
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