Identification of potential therapeutic drugs for huntington's disease using Caenorhabditis elegans.
The prolonged time course of Huntington's disease (HD) neurodegeneration increases both the time and cost of testing potential therapeutic compounds in mammalian models. An alternative is to initially assess the efficacy of compounds in invertebrate models, reducing time of testing from months...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-06-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC1876812?pdf=render |