Allylpyrocatechol, isolated from betel leaf ameliorates thyrotoxicosis in rats by altering thyroid peroxidase and thyrotropin receptors

Abstract Allylpyrocatechol (APC) was isolated from betel leaf and its possible role in L-thyroxin (L-T4)-induced thyrotoxic rats was evaluated. The disease condition, thyrotoxicosis was confirmed by higher levels of thyroid hormones and low thyrotropin (TSH) in serum. Increased hepatic activities of...

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Bibliographic Details
Main Authors: Sunanda Panda, Malabika Sikdar, Sagarika Biswas, Rajesh Sharma, Anand Kar
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-48653-9