SARS-CoV-2-specific circulating T follicular helper cells correlate with neutralizing antibodies and increase during early convalescence.

SARS-CoV-2-specific circulating T follicular helper cells correlate with neutralizing antibodies and increase during early convalescence.

T-cell immunity is likely to play a role in protection against SARS-CoV-2 by helping generate neutralizing antibodies. We longitudinally studied CD4 T-cell responses to the M, N, and S structural proteins of SARS-CoV-2 in 26 convalescent individuals. Within the first two months following symptom ons...

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Bibliographic Details
Main Authors: Sushma Boppana, Kai Qin, Jacob K Files, Ronnie M Russell, Regina Stoltz, Frederic Bibollet-Ruche, Anju Bansal, Nathan Erdmann, Beatrice H Hahn, Paul A Goepfert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009761

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https://doi.org/10.1371/journal.ppat.1009761

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