<i>Aesculus hippocastanum</i> L. Extract Does Not Induce Fibroblast to Myofibroblast Conversion but Increases Extracellular Matrix Production In Vitro Leading to Increased Wound Tensile Strength in Rats

<i>Aesculus hippocastanum</i> L. Extract Does Not Induce Fibroblast to Myofibroblast Conversion but Increases Extracellular Matrix Production In Vitro Leading to Increased Wound Tensile Strength in Rats

The ability of horse chestnut extract (HCE) to induce contraction force in fibroblasts, a process with remarkable significance in skin repair, motivated us to evaluate its wound healing potential in a series of experiments. In the in vitro study of the ability of human dermal fibroblasts to form myo...

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Bibliographic Details
Main Authors: Ivan Kováč, Nikola Melegová, Matúš Čoma, Peter Takáč, Katarína Kováčová, Martin Hollý, Ján Ďurkáč, Lukáš Urban, Miriam Gurbáľová, Emil Švajdlenka, Gabriela Mojžišová, Robert Zajíček, Pavol Szabo, Pavel Mučaji, Peter Gál
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Molecules
Subjects:
wound healing
repair and regeneration
phytotherapy
horse chestnut
Online Access:https://www.mdpi.com/1420-3049/25/8/1917

Internet

https://www.mdpi.com/1420-3049/25/8/1917

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