Examination of the Efficacy and Cross-Reactivity of a Novel Polyclonal Antibody Targeting the Disintegrin Domain in SVMPs to Neutralize Snake Venom

Examination of the Efficacy and Cross-Reactivity of a Novel Polyclonal Antibody Targeting the Disintegrin Domain in SVMPs to Neutralize Snake Venom

Snake envenomation can result in hemorrhage, local necrosis, swelling, and if not treated properly can lead to adverse systemic effects such as coagulopathy, nephrotoxicity, neurotoxicity, and cardiotoxicity, which can result in death. As such, snake venom metalloproteinases (SVMPs) and disintegrins...

Full description

Bibliographic Details
Main Authors: Shelby S. Szteiter, Ilse N. Diego, Jonathan Ortegon, Eliana Salinas, Abcde Cirilo, Armando Reyes, Oscar Sanchez, Montamas Suntravat, Emelyn Salazar, Elda E. Sánchez, Jacob A. Galan
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Toxins
Subjects:
<i>C. atrox</i>
<i>C. o. helleri</i>
antivenom
disintegrin
SVMP PII/PIII
anti-disintegrin
Online Access:https://www.mdpi.com/2072-6651/13/4/254

Internet

https://www.mdpi.com/2072-6651/13/4/254

Similar Items