Prion Protein Affects Ca2+-Activated K+ Currents in Cerebellar Purkinje Cells

Prion Protein Affects Ca2+-Activated K+ Currents in Cerebellar Purkinje Cells

The prion protein (PrPC) has a primary role in the pathogenesis of transmissible spongiform encephalopathies. Its physiological function is not known yet. Altered late afterhyperpolarization has been observed in hippocampal CA1 pyramidal cells of prion protein-deficient mice (Prnp0/0 mice) presumabl...

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Bibliographic Details
Main Authors:	Jochen W. Herms, Tobias Tings, Stefanie Dunker, Hans A. Kretzschmar
Format:	Article
Language:	English
Published:	Elsevier 2001-04-01
Series:	Neurobiology of Disease
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996100903693

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