Cardiovascular Effects of Trans-4-Methoxy-β-Nitrostyrene in Spontaneously Hypertensive Rats: Comparison With Its Parent Drug β-Nitrostyrene

Cardiovascular Effects of Trans-4-Methoxy-β-Nitrostyrene in Spontaneously Hypertensive Rats: Comparison With Its Parent Drug β-Nitrostyrene

We previously reported that trans-4-methoxy-β-nitrostyrene (T4MN) evoked higher vasorelaxant effects in small resistance arteries from spontaneously hypertensive rats (SHRs) in comparison with its parent drug, the β-nitrostyrene 1-nitro-2-phenylethene (NPe). To further our knowledge of the influence...

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Bibliographic Details
Main Authors: Thayane Rebeca Alves-Santos, Odair Alves Silva, Hicla Stefany Moreira, Rosivaldo Santos Borges, Gloria Pinto Duarte, Pedro Jorges Caldas Magalhães, Saad Lahlou
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Pharmacology
Subjects:
perineural capsaicin pretreatment
sensory C-fibers
trans-4-methoxy-β-nitrostyrene
vago-vagal reflex
β-nitrostyrene
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01407/full

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