The Genetic Architecture of a Congenital Heart Defect Is Related to Its Fitness Cost
In newborns, severe congenital heart defects are rarer than mild ones. This epidemiological relationship between heart defect severity and incidence lacks explanation. Here, an analysis of ~10,000 <i>Nkx2-5</i><sup>+/−</sup> mice from two inbred strain crosses illustrates the...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-08-01
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| Series: | Genes |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4425/12/9/1368 |