Clearance effect of sandblasting and hand scaling on subgingival plaque and their effect on interleukin 1/6/8/10 and MMP8/TIMP1 levels

• Main Author: Lei Li
• Format: Article
• Language: English
• Published: Editorial Board of Journal of Hainan Medical University 2016-09-01
• Series: Journal of Hainan Medical University
• Subjects: Subgingival plaqu; Sandblasting; Interleukin; Matrix metalloproteinase; Tissue inhibitor of metalloproteinase
• Online Access: http://www.hnykdxxb.com/PDF/201618/17.pdf
• ISSN: 1007-1237; 1007-1237

Objective: To study the clearance effect of sandblasting and hand scaling on subgingival plaque and their effect on interleukin 1/6/8/10 and MMP8/TIMP1 levels. Methods: A total of 40 patients with subgingival plaque were selected for study, subgingival plaque of left half mouth received hand scaling and was included in hand scaling group, subgingival plaque of right half mouth received sandblasting scaling and was included in sandblasting group, probing depth (PD) and bleeding on probing (BOP) were assessed and the percentage of closed periodontal pocket was calculate before and after treatment; gingival crevicular fluid was collected after treatment to determine interleukin 1/6/8/10 and MMP8/TIMP1 levels. Results: 7 d and 30 d after treatment, PD and BOP percentage of both groups were lower than those before treatment and the percentage of closed periodontal pocket were higher than those before treatment, the PD and BOP percentage of sandblasting group after treatment were lower than those of hand scaling group and the percentage of closed periodontal pocket was higher than that of hand scaling group; 7 d after treatment, IL-1, -6, -8 and MMP8 levels and MMP8/TIMP1 ratio in gingival crevicular fluid of sandblasting group were significantly lower than those of hand scaling group while IL-10 and TIMP1 levels were significantly higher than those of hand scaling group. Conclusion: Sandblasting scaling has better clearance effect on subgingival plaque than hand scaling, and can adjust the interleukin 1/6/8/10 and MMP8/TIMP1 levels to relieve periodontal tissue inflammation and alveolar bone resorption.