An oral vaccine based on U-Omp19 induces protection against B. abortus mucosal challenge by inducing an adaptive IL-17 immune response in mice.

An oral vaccine based on U-Omp19 induces protection against B. abortus mucosal challenge by inducing an adaptive IL-17 immune response in mice.

As Brucella infections occur mainly through mucosal surfaces, the development of mucosal administered vaccines could be radical for the control of brucellosis. In this work we evaluated the potential of Brucella abortus 19 kDa outer membrane protein (U-Omp19) as an edible subunit vaccine against bru...

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Bibliographic Details
Main Authors: Karina A Pasquevich, Andrés E Ibañez, Lorena M Coria, Clara García Samartino, Silvia M Estein, Astrid Zwerdling, Paula Barrionuevo, Fernanda S Oliveira, Christine Seither, Heribert Warzecha, Sergio C Oliveira, Guillermo H Giambartolomei, Juliana Cassataro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3021544?pdf=render

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http://europepmc.org/articles/PMC3021544?pdf=render

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