Cancer vaccines in the world of immune suppressive monocytes (CD14+HLA-DRlo/neg cells): the gateway to improved responses

Cancer vaccines in the world of immune suppressive monocytes (CD14+HLA-DRlo/neg cells): the gateway to improved responses

Dendritic cells are an important target in cancer immunotherapy based on their critical role in antigen presentation and response to tumor development. The capacity of dendritic cells to stimulate anti-tumor immunity have led investigators to use these cells to mediate anti-tumor responses in a numb...

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Bibliographic Details
Main Authors: Rebecca R Laborde, Yi eLin, Michael eGustafson, Peggy eBulur, Allan B Dietz
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Immunology
Subjects:
Dendritic Cells
Immunotherapy
Monocytes
MDSC
CD14+HLA-DRlo/neg
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00147/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00147/full

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