Palladium-catalyzed intramolecular tandem dearomatization of indoles for the synthesis of tetracyclic indolines

Palladium-catalyzed intramolecular tandem dearomatization of indoles for the synthesis of tetracyclic indolines

A highly diastereoselective, atom-economical, and palladium-catalyzed Heck protocol for the assembly of structurally diverse indoline scaffolds with vicinal tertiary as well as quaternary stereocenters is described, starting from readily available N-halobenzoyl o-haloaniline derivatives and phenylbo...

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Bibliographic Details
Main Authors: Shao-Bo Duan, Xu-Jing Gao, Hong-Yu Zhang, Cong-Cong Lu, Jiquan Zhao, Ya-Ping Han, Yuecheng Zhang, Yong-Min Liang
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Arabian Journal of Chemistry
Subjects:
Tetracyclic indoline derivatives
Palladium-catalyzed
Aryl halides
Phenylboronic acids
Heck reaction
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535221001702

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http://www.sciencedirect.com/science/article/pii/S1878535221001702

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