Peptide Super-Agonist Enhances T-Cell Responses to Melanoma

Peptide Super-Agonist Enhances T-Cell Responses to Melanoma

Recent immunotherapeutic approaches using adoptive cell therapy, or checkpoint blockade, have demonstrated the powerful anti-cancer potential of CD8 cytotoxic T-lymphocytes (CTL). While these approaches have shown great promise, they are only effective in some patients with some cancers. The potenti...

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Bibliographic Details
Main Authors: Sarah A. E. Galloway, Garry Dolton, Meriem Attaf, Aaron Wall, Anna Fuller, Cristina Rius, Valentina Bianchi, Sarah Theaker, Angharad Lloyd, Marine E. Caillaud, Inge Marie Svane, Marco Donia, David K. Cole, Barbara Szomolay, Pierre Rizkallah, Andrew K. Sewell
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
altered peptide ligand
T-cell receptor
melanoma
tumour infiltrating lymphocyte
cancer vaccine
cancer immunotherapy
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00319/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00319/full

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