Predicting the allergenicity of legume proteins using a PBMC gene expression assay

Predicting the allergenicity of legume proteins using a PBMC gene expression assay

Abstract Background Food proteins differ in their allergenic potential. Currently, there is no predictive and validated bio-assay to evaluate the allergenicity of novel food proteins. The objective of this study was to investigate the potential of a human peripheral blood mononuclear cell (PBMC) gen...

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Bibliographic Details
Main Authors: Mark Smits, Marjolein Meijerink, Thuy-My Le, André Knulst, Aard de Jong, Martinus Petrus Maria Caspers, Everton Souto Lima, Lilia Babé, Gregory Ladics, Scott McClain, Geert Houben, Kitty Verhoeckx
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Immunology
Subjects:
Food allergy
Allergenicity prediction assay
Allergenic legume protein pairs
Biomarker discovery
Graded allergenic response
Online Access:https://doi.org/10.1186/s12865-021-00415-x

Internet

https://doi.org/10.1186/s12865-021-00415-x

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